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Invention, like scientific discovery, sometimes occurs through a heuristic search process where an inventor seeks a successful invention by searching through a space of inventions. For complex inventions, such as the airplane or model rockets, the process of invention can be expedited by an appropriate strategy of invention. Two case studies will be used to illustrate these general principles: the...
Development of high throughput data acquisition technologies, together with advances in computing, and communications have resulted in an explosive growth in the number, size, and diversity of potentially useful information sources. This has resulted in unprecedented opportunities in data-driven knowledge acquisition and decision-making in a number of emerging increasingly data-rich application domains...
This article gives a comprehensive study on SMO-type (Sequential Minimal Optimization) decomposition methods for training support vector machines. We propose a general and flexible selection of the two-element working set. Main theoretical results include 1) a simple asymptotic convergence proof, 2) a useful explanation of the shrinking and caching techniques, and 3) the linear convergence of this...
We are interested in the automation of science for both philosophical and technological reasons. To this end we have built the first automated system that is capable of automatically: originating hypotheses to explain data, devising experiments to test these hypotheses, physically running these experiments using a laboratory robot, interpreting the results, and then repeat the cycle. We call such...
In the 1980s, Don Swanson proposed the concept of “undiscovered public knowledge,” and published several examples in which two disparate literatures (i.e., sets of articles having no papers in common, no authors in common, and few cross-citations) nevertheless held complementary pieces of knowledge that, when brought together, made compelling and testable predictions about potential therapies for...
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